Serial o lekarzach, na podstawie książki. Codziennie chirurdzy z Portland walczą o życie pacjentów i próbują połączyć swój trudny zawód z prywatnymi ambicjami.
Chelsea General is home to some of the top surgeons in the world, thanks in large part to the hospital's notorious Monday morning morbidity and mortality - or "311" - conferences. In these legendary meetings, Chief of Staff Harding Hooten (Alfred Molina) leads a harsh, closed-door review of the complications encountered and mistakes made during the course of patient care.
Sung, Hooten and Villanueva join forces to convince Trisha Miller (guest star Cozi Zuehlsdorff), a 13-year-old girl with an advanced brain stem glioma, to try surgery one last time before giving up.
Sung is forced to meet with Risk Management's Fran Horowitz (guest star Valerie Mahaffey) after refusing to apologize to the wife of a patient who died on his table.
Hooten's mentor, Dr. Arvin Wayne (guest star Hal Holbrook), walks into the wrong procedure on the wrong day, leading the surgeons at Chelsea General to question the cognitive abilities of one of the hospital's elder statesmen.
Ty and Tina receive a late night call from Afghanistan, where Corpsman Jacob Gold (guest star Reiley McClendon) desperately needs help when his fellow Marine suffers a traumatic head injury.
During Monday's 311 conference, Hooten calls Dr. Stewart Delany (guest star Ioan Gruffund) to explain how a careless mistake killed Delany's young patient. But the outcome of the conference leaves the hospital's surgeons conflicted.
Ty and Hooten believe Supreme Court hopeful Judge Beverly Nathenson's facial pain is the result of a brain tumor; upon operating, the surgeons discover a diagnosis much more shocking.
Hooten and Buck find themselves facing off in court against attorney Mitch Tompkins (guest star Anthony Heald) after a grieving son refuses to comply with his mother's final wishes. Sydney's outrage over the health of a morbidly obese 16-year-old boy further strains her relationship with Lieberman (guest star Jonathan Silverman).