Euforia oparta jest na izraelskim formacie o tym samym tytule i powiada o losach grupy licealistów, którzy walczą z problemami w świecie narkotyków, seksu, social mediów i osobistych traum.
Rue returns home from rehab and meets Jules; Nate gets in McKay's head when he takes an interest in Cassie; Nate and Maddy attempt to make each other jealous; Kat is pressured to lose something.
First day of school, Rue's struggles to put the past behind her; Nate becomes obsessed with Maddy's hookup; Kat finds a video of her has surfaced online; McKay takes the stress of college out on Cassie.
Kat tries her first camming session; Jules starts falling for a boy online; Maddy finds something odd on Nate's phone; Cassie and McKay spend the weekend at his school; Rue is confronted about her lies at NA.
Rue tries to get clean for Jules and chaperones Gia at the carnival; Cassie and Maddy decide to do molly together; Kat hangs out with Ethan until she misreads a situation; Nate reveals who he really is.
In the aftermath of the carnival, Maddy and Nate are forced to deal with a police investigation; Jules begins to feel pressured by her role in Rue's sobriety; Cal worries about how his actions have affected his sons.
On Halloween, Rue worries about her reliance on Jules when she starts exhibiting concerning behavior; McKay questions his future in football; Kat continues to push Ethan away; Nate comes up with a plan to get his life back on track.